The Mediating Role of Cortical Thickness and Gray Matter Volume on Sleep During Adolescence
Adolescence is a period of human development that involves a myriad of biological and behavioral changes, influenced by a myriad of factors including physical growth, puberty and complex changes to the brain structure, function and connectivity. Dramatic changes to sleep architecture also occur. Reductions occur in cortical thickness and gray matter volume (which processes muscle control and sensory perception), along with a 65% reduction in slow wave (delta) activity during sleep. Yet, research is light on empirical data linking structural brain changes and functional sleep differences. This article published in Brain Structure and Function investigates whether age-related differences in cortical thickness and gray matter volume and cortical thickness account for typical age-related differences in slow wave (delta) activity.